5-Methyl-4-sulfamoyl-thiophene-3-carboxylic acid methyl ester
Methyl 4-(aminosulfonyl)-5-methylthiophene-3-carboxylate
CAS: 317815-81-9
Molecular Formula: C7H9NO4S2
5-Methyl-4-sulfamoyl-thiophene-3-carboxylic acid methyl ester - Names and Identifiers
5-Methyl-4-sulfamoyl-thiophene-3-carboxylic acid methyl ester - Physico-chemical Properties
| Molecular Formula | C7H9NO4S2 |
| Molar Mass | 235.28 |
| Density | 1.452±0.06 g/cm3(Predicted) |
| Boling Point | 431.2±55.0 °C(Predicted) |
| pKa | 9?+-.0.60(Predicted) |
5-Methyl-4-sulfamoyl-thiophene-3-carboxylic acid methyl ester - Introduction
Methyl 4-(aminossulfonyl)-is an organic compound with the chemical formula C8H9NO4S2. The following is a description of some properties, uses, preparation and safety information about this compound:
Nature:
-Appearance: It is a white to light yellow crystal or crystalline powder.
-Solubility: It can be dissolved in some organic solvents, such as ethanol, ether and chloroform. It is hardly soluble in water.
-Melting point: About 116-120 ° C.
-Stability: It is stable at room temperature, but it will decompose when heated.
Use:
- Methyl 4-(aminosulfonyl)-is often used as a reagent or intermediate in organic synthesis.
-It can be used to synthesize other organic compounds, such as drugs, dyes and functional materials.
Method:
The preparation of-Methyl 4-(aminosulfonyl)-is usually obtained by The electrophilic substitution reaction of the compound 5-Methyl -4-thiophenol. First, in the presence of concentrated sulfuric acid, the alcohol group reacts with an electrophile (such as sodium hypochlorite) to produce the corresponding coprime. Then, the interprime is reacted with the sulfamic acid to obtain the product.
Safety Information:
- Methyl 4-(aminosulfonyl)-The impact on health and safety has not been fully evaluated, so use and handle with caution.
-It should avoid contact with the skin and avoid inhaling its dust or vapor.
-Pay attention to the correct protective measures during operation, such as wearing protective glasses, gloves and protective clothing.
-When using or storing, keep it away from fire and oxidant to avoid fire or explosion.
-In case of accidental inhalation or contact, seek medical attention immediately and give the container or label to a doctor.
Nature:
-Appearance: It is a white to light yellow crystal or crystalline powder.
-Solubility: It can be dissolved in some organic solvents, such as ethanol, ether and chloroform. It is hardly soluble in water.
-Melting point: About 116-120 ° C.
-Stability: It is stable at room temperature, but it will decompose when heated.
Use:
- Methyl 4-(aminosulfonyl)-is often used as a reagent or intermediate in organic synthesis.
-It can be used to synthesize other organic compounds, such as drugs, dyes and functional materials.
Method:
The preparation of-Methyl 4-(aminosulfonyl)-is usually obtained by The electrophilic substitution reaction of the compound 5-Methyl -4-thiophenol. First, in the presence of concentrated sulfuric acid, the alcohol group reacts with an electrophile (such as sodium hypochlorite) to produce the corresponding coprime. Then, the interprime is reacted with the sulfamic acid to obtain the product.
Safety Information:
- Methyl 4-(aminosulfonyl)-The impact on health and safety has not been fully evaluated, so use and handle with caution.
-It should avoid contact with the skin and avoid inhaling its dust or vapor.
-Pay attention to the correct protective measures during operation, such as wearing protective glasses, gloves and protective clothing.
-When using or storing, keep it away from fire and oxidant to avoid fire or explosion.
-In case of accidental inhalation or contact, seek medical attention immediately and give the container or label to a doctor.
Last Update：2024-04-09 21:01:54
